IN VITRO PRE-CLINICAL TESTING OPERATIONS
Receive specific cultures from authentic validated sources. KamTek is registered with BEI-NIAID program at ATCC to receive a wide variety of fully characterized microbial cultures as glycerol stocks for research purposes. In addition, KamTek establishes collaborative arrangements with academic labs that specialize in isolating and characterizing specific microbes. Alternatively, clients provide their own microbes for any of the following operations. From these sources cultures could arrive as cryo-preserved stocks or live cultures. KamTek is however, not set up for "Select Agents" and does not receive those agents.
Revive, expand, and cryopreserve microbial cultures as glycerol stocks or spore stocks for long term cryo-storage and subsequent experimental use.
KamTek staff is fully trained and lab is fully equipped to handle both anaerobic and aerobic biosafety class II microbes. Regularly performed operations include:
Study anti-microbial activity of investigational compounds. KamTek staff performs in vitro determinations of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of investigational compounds on regular basis. These determinations are made both on target bacteria and other bacteria to establish their real clinical utility. Depending on the requirements, the following operations are also carried out:
The lab is equipped with a Bactron EZ (Shell Labs) anaerobic chamber for handling anaerobic bacteria, with a BSL-2 Class II laminar flow hood for handling aerobic bacteria, an autoclave reagent and labware sterilizations as well as inactivating live microbes before discarding.
IN VIVO PRE-CLINICAL TESTING SERVICES